Expression of Genes Encoding Serotonin Receptors and SERT in Various Brain Structures of Stressed Rats after Chronic Exposure to Ultrasound
作者： A Yu Morozova , EA Zubkov , FA Koshkin , ZI Storozheva , VP Chekhonin
DOI: 10.1007/S10517-014-2338-Y
关键词: Endocrinology 、 Prefrontal cortex 、 Biology 、 Chronic stress 、 Receptor 、 Internal medicine 、 Hippocampus 、 Serotonin transporter 、 Gene expression 、 Serotonergic 、 5-HT receptor
摘要: The expression of genes encoding serotonin receptors and transporter in emotiogenic structures rat brain was shown to change after chronic stress with ultrasonic waves varying frequencies. A QPCR-RT study revealed the increased for SERT 5-HT1B receptor decreased 5-HT2A prefrontal cortex rats exposure Gene SERT, but 5-HT1B, 5-HT2A, 5-HT2B midbrain animals. hippocampus characterized by an 5-HT1A, receptors. Our results indicate that this type is followed dysregulation serotoninergic system brain.
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