Effect of Ultrasonic Irradiation on the Development of Symptoms of Depression and Anxiety in Rats
作者： A. Yu. Morozova , E. A. Zubkov , Z. I. Storozheva , Z. I. Kekelidze , V. P. Chekhonin
DOI: 10.1007/S10517-013-2044-1
关键词:
摘要: Behavioral reactions of rats were studied under conditions constant exposure to ultrasonic irradiation at a frequency 20-45 kHz for 21 days. In subjected ultrasound, impaired behavior in the social interest test and Porsolt forced swimming was observed; development anhedonia sucrose preference revealed (manifested symptoms depression). The effects abolished by an antidepressant fluoxetine, selective serotonin reuptake inhibitor. Our results indicate that chronic radiation produces modulatory effect on depressive rats. These changes satisfy requirements experimental animals, which are used as model psychopathological processes.
springer.com
sci-hub.se 参考文章(8)
Paul Willner, Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation Psychopharmacology. ,vol. 134, pp. 319- 329 ,(1997) , 10.1007/S002130050456
Alessia Bachis, Maria Idalia Cruz, Rachel L. Nosheny, Italo Mocchetti, Chronic Unpredictable Stress Promotes Neuronal Apoptosis in the Cerebral Cortex Neuroscience Letters. ,vol. 442, pp. 104- 108 ,(2008) , 10.1016/J.NEULET.2008.06.081
William T. McKinney, Overview of the past contributions of animal models and their changing place in psychiatry. Seminars in Clinical Neuropsychiatry. ,vol. 6, pp. 68- 78 ,(2001) , 10.1053/SCNP.2001.20292
Leslie Matuszewich, Jared J. Karney, Samantha R. Carter, Steven P. Janasik, Johanna L. O'Brien, Ross D. Friedman, THE DELAYED EFFECTS OF CHRONIC UNPREDICTABLE STRESS ON ANXIETY MEASURES Physiology & Behavior. ,vol. 90, pp. 674- 681 ,(2007) , 10.1016/J.PHYSBEH.2006.12.006
Benedetto Vitiello, Treatment of adolescent depression: what we have come to know Depression and Anxiety. ,vol. 26, pp. 393- 395 ,(2009) , 10.1002/DA.20572
Nobuaki Takahashi, Makio Kashino, Naoyuki Hironaka, Structure of Rat Ultrasonic Vocalizations and Its Relevance to Behavior PLoS ONE. ,vol. 5, pp. e14115- ,(2010) , 10.1371/JOURNAL.PONE.0014115
Brittney M. Cox, Fares Alsawah, Peter C. McNeill, Matthew P. Galloway, Shane A. Perrine, Neurochemical, hormonal, and behavioral effects of chronic unpredictable stress in the rat. Behavioural Brain Research. ,vol. 220, pp. 106- 111 ,(2011) , 10.1016/J.BBR.2011.01.038
F Josef van der Staay, Saskia S Arndt, Rebecca E Nordquist, Evaluation of animal models of neurobehavioral disorders Behavioral and Brain Functions. ,vol. 5, pp. 11- 11 ,(2009) , 10.1186/1744-9081-5-11