What is the Helicobacter pylori global reinfection rate

摘要: Since the initiation of Helicobacter pylori treatment in 1980s, concerns have been raised that high reinfection rates might mitigate against H. treatment. Reinfection has particular concern where primary infection are also high, i.e. developing countries. In Bangladesh and Brazil, studies indicated annual rates, investigators expressed pessimism about long-term benefits1,2. Even developed countries such as United States, however, rate a concern. Given with multiple strains is relatively common, likelihood following seems particularly plausible3. If those who actively infected can be reinfected, what to prevent phenomenon recently treated patients? Knowing provides important data on natural acquisition host immunity, providing insights into vaccine development other immunological therapies. Moreover, from pathophysiological standpoint, distinguishing recrudescence unsuccessfully permits us better delineate best antimicrobial strategies.