Low incidence of malignancy among sirolimus/cyclosporine-treated renal transplant recipients

作者: Barry D Kahan , Yarkin K Yakupoglu , Linda Schoenberg , Richard J Knight , Stephen M Katz

DOI: 10.1097/01.TP.0000173770.42403.F7

关键词: SirolimusGastroenterologyKidneyInternal medicineNephrectomyPrednisoneIncidence (epidemiology)PopulationImmunosuppressionMedicineSurgeryKidney transplantation

摘要: … therapy display a significantly increased incidence of … of agents that display antineoplastic properties concomitant … ( 27 ) showed that sirolimus displays antitumor activity: namely, it …

参考文章(42)
Gregory J. Wiederrecht, Candace J. Sabers, Gregory J. Brunn, Mary M. Martin, Francis J. Dumont, Robert T. Abraham, Mechanism of action of rapamycin: New insights into the regulation of G1-phase progression in eukaryotic cells Progress in cell cycle research. ,vol. 1, pp. 53- 71 ,(1995) , 10.1007/978-1-4615-1809-9_5
Penn I, Cancers in cyclosporine-treated vs azathioprine-treated patients. Transplantation proceedings. ,vol. 28, pp. 876- ,(1996)
Anne-Karina Perl, Petra Wilgenbus, Ulf Dahl, Henrik Semb, Gerhard Christofori, A causal role for E-cadherin in the transition from adenoma to carcinoma Nature. ,vol. 392, pp. 190- 193 ,(1998) , 10.1038/32433
Minoru Hojo, Takashi Morimoto, Mary Maluccio, Tomohiko Asano, Kengo Morimoto, Milagros Lagman, Toshikazu Shimbo, Manikkam Suthanthiran, Cyclosporine induces cancer progression by a cell-autonomous mechanism Nature. ,vol. 397, pp. 530- 534 ,(1999) , 10.1038/17401
Dixon B. Kaufman, Ron Shapiro, Michael R. Lucey, Wida S. Cherikh, Rami T. Bustami, David B. Dyke, Immunosuppression: practice and trends American Journal of Transplantation. ,vol. 4, pp. 38- 53 ,(2003) , 10.1111/J.1600-6135.2004.00397.X
Peter J. Houghton, Hajime Hosoi, Michael B. Dilling, Glen S. Germain, Lili Shu, Robert T. Abraham, Linda N. Liu, Takuma Shikata, Richard A. Ashmun, Rapamycin Causes Poorly Reversible Inhibition of mTOR and Induces p53-independent Apoptosis in Human Rhabdomyosarcoma Cells Cancer Research. ,vol. 59, pp. 886- 894 ,(1999)
Israel Penn, Primary kidney tumors before and after renal transplantation. Transplantation. ,vol. 59, pp. 480- 485 ,(1995) , 10.1097/00007890-199502270-00006
A.D Hibberd, P.R Trevillian, J.H Wlodarzcyk, A.H.B Gillies, A.M Stein, A.G.R Sheil, A.P.S Disney, Cancer risk associated with ATG/OKT3 in renal transplantation. World Congress of the Transplantation Society. ,vol. 31, pp. 1271- 1272 ,(1999) , 10.1016/S0041-1345(98)01992-7