Aspartame and Soft Drink-Mediated Neurotoxicity in Rats: Implication of Oxidative Stress, Apoptotic Signaling Pathways, Electrolytes and Hormonal Levels
作者： Mohamed A. Lebda , Kadry M. Sadek , Yasser S. El-Sayed
DOI: 10.1007/S11011-017-0052-Y
关键词: Brain damage 、 Glutathione 、 Lipid peroxidation 、 Malondialdehyde 、 Endocrinology 、 Oxidative phosphorylation 、 Oxidative stress 、 Neurotoxicity 、 Internal medicine 、 Aspartame 、 Chemistry
摘要: … Additionally, significant increment of acetylcholine esterase activity … across mitochondrial membrane resulted in osmotic swelling of mitochondria and rupture of the outer mitochondrial …
springer.com
sci-hub.se 参考文章(60)
Fei Xiao, Li Yang, Chaoxu Wang, Effects of copper deficiency on iron metabolism in rats Journal of hygiene research. ,vol. 42, pp. 652- 655 ,(2013)
Theo Wallimann, Introduction--creatine: cheap ergogenic supplement with great potential for health and disease. Sub-cellular biochemistry. ,vol. 46, pp. 1- 16 ,(2007) , 10.1007/978-1-4020-6486-9_1
Oluwatosin A. Adaramoye, Olubukola O. Akanni, Effects of long-term administration of aspartame on biochemical indices, lipid profile and redox status of cellular system of male rats. Journal of basic and clinical physiology and pharmacology. ,vol. 27, pp. 29- 37 ,(2016) , 10.1515/JBCPP-2014-0130
William H. Habig, Michael J. Pabst, William B. Jakoby, Glutathione S-Transferases Journal of Biological Chemistry. ,vol. 249, pp. 7130- 7139 ,(1974) , 10.1016/S0021-9258(19)42083-8
M Abhilash, MV Sauganth Paul, Mathews V Varghese, R Harikumaran Nair, None, Long-term consumption of aspartame and brain antioxidant defense status. Drug and Chemical Toxicology. ,vol. 36, pp. 135- 140 ,(2013) , 10.3109/01480545.2012.658403
Takae Hirasawa, Takeshi Nakamura, Akiko Mizushima, Mitsuhiro Morita, Ikuko Ezawa, Hiroyoshi Miyakawa, Yoshihisa Kudo, Adverse effects of an active fragment of parathyroid hormone on rat hippocampal organotypic cultures British Journal of Pharmacology. ,vol. 129, pp. 21- 28 ,(2000) , 10.1038/SJ.BJP.0702949
The role of creatine kinase in inhibition of mitochondrial permeability transition. FEBS Letters. ,vol. 414, pp. 253- 257 ,(1997) , 10.1016/S0014-5793(97)01045-4
Iyaswamy Ashok, Rathinasamy Sheeladevi, Biochemical responses and mitochondrial mediated activation of apoptosis on long-term effect of aspartame in rat brain Redox biology. ,vol. 2, pp. 820- 831 ,(2014) , 10.1016/J.REDOX.2014.04.011
Hiroshi Ohkawa, Nobuko Ohishi, Kunio Yagi, Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Analytical Biochemistry. ,vol. 95, pp. 351- 358 ,(1979) , 10.1016/0003-2697(79)90738-3
Eef Hogervorst, Felicia Huppert, Fiona E. Matthews, Carol Brayne, Thyroid function and cognitive decline in the MRC Cognitive Function and Ageing Study Psychoneuroendocrinology. ,vol. 33, pp. 1013- 1022 ,(2008) , 10.1016/J.PSYNEUEN.2008.05.008