Antihyperglycemic activity of compounds isolated from Indian medicinal plants
作者： Akanksha , Rakesh Maurya , Arvind K. Srivastava
DOI:
关键词: In vitro system 、 Metformin 、 Medicinal plants 、 Diabetic rat 、 Traditional medicine 、 Medicine 、 Drug 、 Streptozotocin
摘要: Eleven antidiabetic Indian medicinal plants were investigated in streptozotocin induced diabetic rat model and provided scientific validation to prove their antihyperglycemic activity. Antidiabetic principles from five isolated. All the compounds isolated evaluated for activity activities compared with standard drug metformin. Some also screened db/db mice. Two (PP-1 PP-2) inhibited significantly of PTPase-1B an vitro system. This might be underlying mechanism these compounds.
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