The distribution of fibronectin and P component in Descemet's membrane: an immunoelectron microscopic study

作者: S. G. Levy , A. C. E. McCartney , J. Moss

DOI: 10.3109/02713689508995810

关键词: Eye bankImmunogold labellingFibronectinAnatomyDescemet's membraneMatrix (biology)Immunoelectron microscopyChemistryCorneal endotheliumUltrastructureOphthalmologySensory SystemsCellular and Molecular Neuroscience

摘要: Descemet's membrane consists of two zones, the ‘anterior banded zone’ which contains wide-spaced collagen and amorphous ‘posterior non-banded zone’. It is attached anteriorly to corneal stroma by a narrow transitional zone termed ‘interfacial matrix’.The distribution fibronectin P component within different layers was investigated using an ultrastructural immunogold technique. Seven normal human corneas from eye bank one specimen orbital exenteration were examined.Fibronectin predominantly present in posterior part anterior zone. The contained less fibronectin. throughout zones. There sharp demarcation at interfacial matrix since neither substance observed stroma.The differences shown Des...

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