作者: Jun-Yao Li
DOI: 10.1007/978-1-4612-5006-7_21
关键词: Esophageal cancer 、 China 、 Internal medicine 、 Population 、 Cancer 、 Oncology 、 Esophagus 、 Incidence (epidemiology) 、 Vitamin 、 Mortality rate 、 Environmental health 、 Medicine
摘要: The highest worldwide incidence and mortality for cancer of the esophagus occurs in China.(1,2) Linxian, Henan Province, is epicenter this maligancy may indeed be world’s risk area, where cumulative death rates (0–74yr) are 32.5% males 20.4% females. Reasons such exceptional esophageal not yet known, but a series investigations carried out Linxian suggests that population enhanced susceptibility to specific carcinogens because deficiencies multiple nutrients, especially vitamins minerals. (3,4,5) To test an hypothesis vitamin/mineral contribute Linxian’ s high supplementation reduce risk, Cancer Institute, Chinese Academy Medical Sciences collaboration with National NIH, U.S.A. carring two intervention trials using vitamin-mineral supplements. One trial will conducted patients diagnosed dysplasia other general population.