Guidance on management of asymptomatic neonates born to women with active genital herpes lesions.

作者: David W Kimberlin , Jill Baley , Committee on Infectious Diseases , Committee on Fetus and Newborn , Michael T Brady

DOI: 10.1542/PEDS.2012-3216

关键词: AsymptomaticHSL and HSVTransmission (medicine)ImmunologyMedicineViral sheddingSerologyAsymptomatic DiseasesHerpes simplex virusVirus

摘要: Herpes simplex virus (HSV) infection of the neonate is uncommon, but genital herpes infections in adults are very common. Thus, although treating an infant with neonatal a relatively rare occurrence, managing infants potentially exposed to HSV at time delivery occurs more frequently. The risk transmitting during determined part by mother’s previous immunity HSV. Women primary who shedding 10 30 times likely transmit their newborn than women recurrent delivery. With availability commercial serological tests that reliably can distinguish type-specific antibodies, it now possible determine type maternal and, thus, further refine management delivered have active lesions. algorithm presented herein uses both and virological studies transmission mother herpetic lesions tailors accordingly. does not address approach asymptomatic neonates history no

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