The use of biological therapy in cancer of the head and neck.

摘要: Exciting progress, in the molecular and cell biology of head neck cancer has provided us with new ways to target cells more specifically. The possibility now exists gene therapy targeting specific genetic defects found certain tumor types using any one a number possible delivery systems. Although problems currently existing strategies remain be addressed, encouraging preclinical clinical data indicate that this is very promising area. In addition, exquisite sensitivity anti/bodies directed at targets should make antibody-conjugated toxins, radioimmunoconjugates, antibodies alone viable therapeutic options. Finally, increased understanding antitumor immune response yielded rationally designed cytokine as well cellular-based immunologic treatments for cancer. During next several years, physicians scientists alike will need critically appraise results trials some these novel treatment approaches determine how they fit options patients Given tumors arise from multiple aberrations, it likely biological therapies used combination other or conventional modalities.