Vaccination therapies in solid tumors

作者: Alfonsus J. M. van den Eertwegh

DOI: 10.1007/3-7643-7407-1_5

关键词: ImmunotherapyCetuximabEpidermal growth factor receptorAutologous tumor cellMedicineMonoclonal antibodyCancer researchAntibodyAntigenCancer

摘要: Over the last two decades there has been a great deal of interest in specific immunotherapies. Particularly field passive immunotherapy, using tumor-specific antibodies, some interesting successes have reported. The humanized monoclonal antibody, Herceptin, directed to Her-2-neu antigen is now an established standard modality treatment breast cancer patients, whose tumor overexpressing [1]. Cetuximab, antibody for another epidermal growth factor receptor, about be registered metastatic colon [2]. with anti-CD20 antibodies improves prognosis lymphoma patients and considered as immunotherapy B cell lymphomas [3]. All together it took more than 30 years before evolved cancer. It important realize that was no 10 ago perspectives this type were not so promising. humanization real breakthrough opened way treatment.

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