作者: Fouad A. Siddiqi
DOI:
关键词: Opioid 、 Chronic diarrhea 、 Defecation 、 Mast cell activation 、 Diarrhea 、 Pharmacology 、 Medicine
摘要: The present invention is directed to methods of treatment and/or management diarrhea, such as chronic diarrhea using sequential administration opioid agonists suppress gut mobility and antagonists reverse the effect controllably allow bowel movements. are administered with a time interval in between or release drugs from pharmaceutical composition. further controlling, treating managing side effects caused by agonists, specifically resulting mast cell activation granulation.