Tumour evolution inferred by single-cell sequencing
作者： Nicholas Navin , Jude Kendall , Jennifer Troge , Peter Andrews , Linda Rodgers
DOI: 10.1038/NATURE09807
关键词: Genetic heterogeneity 、 DNA sequencing 、 Evolutionary biology 、 MALBAC 、 Copy-number variation 、 Single-cell analysis 、 Genetics 、 Biology 、 Single cell sequencing 、 Genomics 、 Pseudodiploid
摘要: … a single cell, sufficient to quantify copy number from sequence … These sequences were mapped back to the human reference … For a single cell we typically measure 138 sequence reads …
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