Infection, Bacteremia, Sepsis, and the Sepsis Syndrome: Metabolic Alterations, Hypermetabolism, and Cellular Alterations

摘要: The term “sepsis syndrome” describes a systemic inflammatory and hypermetabolic response of the body on cellular, organ, organ systems level to variety microbial stimuli other than exogenous agents. latter may include but are not limited accidental blunt penetrating injuries, surgical trauma, burns, pancreatitis, bowel disease, others. If bacteria, viruses, or fungi involved sepsis syndrome is caused by these microbes, “sepsis” used. Systemic (SIRS) an expression that has been used recently as common denominator for such states independent their cause. Infection denotes (locally confined) presence microorganisms invasion normally sterile host tissue those organisms, “bacteremia” means bacteria in bloodstream, indicating infectious focus with spillover into circulation. Conditions viremia fungemia can be similarly defined.1, 2