Benign Tracheal Stenosis Should Never be Stented With Metallic Devices

摘要: In this issue of Archivos de Bronconeumologia Serrano et al.1 report the results an elegant experimental study on rabbit trachea. The authors hypothesise that drug-eluting stents attenuate granuloma formation leading to inflammatory stenosis, which is a well-known adverse effect metallic tracheal epithelium. As commented by in text, 2005 US Food and Drug Administration alerted healthcare professionals “to serious complications associated with use patients benign airway disorders. . .including all covered uncovered stents”.2 safety alert for medical products, potential were described as “obstructive granulation tissue, stenosis at ends stent, migration mucous plugging, infection, stent fracture”. Moreover, notification against bridge definitive therapies due risks removal. FDA recommendations are supported authors’ data. their series, 40% cases (14 out 30 animals) died result procedure. mortality obstruction occurred 80% (8/10 rabbits). Therefore, we totally agree main conclusion: steel should never be indicated treatment stenosis. second conclusion investigation (nitinol least reactive) arguable, reported different manner, since 20% nitinol stent-treated (2 10) obstruction. This would non-acceptable rate events clinical series. Thus, it clearly stated used inside healthy trachea, setting, cases. airways has been rarely reported. Chao al.3 implanted biodegradable cis-platinum