Tracheal self-expandable metallic stents: A comparative study of three different stents in a rabbit model
作者： Carolina Serrano , Fernando Lostalé , Francisco Rodríguez-Panadero , Ignacio de Blas , Alicia Laborda
DOI: 10.1016/J.ARBR.2015.06.012
关键词:
摘要: Abstract Introduction The objective of this study was to assess tracheal reactivity after the deployment different self-expandable metal stents (SEMS). Material and methods Forty female New Zealand rabbits were divided into four groups. Three groups received three SEMS: steel (ST), nitinol (NiTi), or drug-eluting stent (DES); fourth group control (no stent). Stents deployed percutaneously under fluoroscopic guidance. Animals assessed by multi-slice, computed tomography (CT) scans, tracheas collected for anatomical pathology (AP) study. Data from CT AP statistically analyzed correlated. Results DES had longest stenosis (20.51 ± 14.08 mm vs 5.84 ± 12.43 6.57 ± 6.54 mm in NiTi ST, respectively, day 30; P revealed that ST developed intense proliferative compared other In group, a destructive response observed 70% animals, while least reactive stent. more effective detecting wall thickening (positive correlation 68.9%; Conclusions granulomas significant stenosis. stent, caused lesions may be related drug dosage. This type is therefore not recommended treatment tracheobronchial
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