The association between vascular risk factors and lower urinary tract symptoms in both sexes.

作者: Anton Ponholzer , Christian Temml , Clemens Wehrberger , Martin Marszalek , Stephan Madersbacher

DOI: 10.1016/J.EURURO.2006.01.031

关键词: Vascular diseaseComorbidityDiabetes mellitusSurgeryMedicineInternal medicineRisk factorLower urinary tract symptomsSex characteristicsInternational Prostate Symptom ScoreMass screening

摘要: Abstract Objectives To test the potential role of atherosclerosis in development lower urinary tract symptoms (LUTS), we investigated association between vascular risk factors and LUTS both sexes. Methods Men women participating a health screening project completed International Prostate Symptom Score (IPSS). In parallel all individuals underwent detailed investigation with assessment diabetes mellitus, hypertension, hyperlipidemia, nicotine use. Results A total 1724 men (52.3±9.1yr, mean±standard deviation; IPSS: 6.3±4.3) 812 (56.0±9.9 yr; 5.2±4.9) entered study. 62.5% ( n =1077) had no factor, 32.1% =554) one, 5.4% =93) two or more; corresponding figures for were 64.7% =525), 30.7% =249), 4.7% =38). men, IPSS was identical those (6.2±4.1) one (6.2±4.4) factor yet increased to 7.7±5.5 (+24.2%) more p =0.01). women, from 4.8±4.6 5.7±5.3 (+18.7%) 7.0±5.7 (+45.8%) =0.05). Conclusions Our data suggest that play This observation opens new aspects our understanding pathogenesis warrants future studies.

参考文章(25)
Kazem M. Azadzoi, Effect of Chronic Ischemia on Bladder Structure and Function Advances in Experimental Medicine and Biology. ,vol. 539, pp. 271- 280 ,(2003) , 10.1007/978-1-4419-8889-8_19
P. Boyle, C. Robertson, C. Mazzetta, M. Keech, F.D.R. Hobbs, R. Fourcade, L. Kiemeney, C. Lee, , The prevalence of lower urinary tract symptoms in men and women in four centres. The UrEpik study. BJUI. ,vol. 92, pp. 409- 414 ,(2003) , 10.1046/J.1464-410X.2003.04369.X
Kevin T. McVary, Erectile Dysfunction and Lower Urinary Tract Symptoms Secondary to BPH European Urology. ,vol. 47, pp. 838- 845 ,(2005) , 10.1016/J.EURURO.2005.02.001
Georg Schatzl, Christian Temml, Julia Waldmüller, Thomas Thürridl, Gerald Haidinger, Stephan Madersbacher, A comparative cross-sectional study of lower urinary tract symptoms in both sexes. European Urology. ,vol. 40, pp. 213- 219 ,(2001) , 10.1159/000049775
Stephan Madersbacher, Armin Pycha, Georg Schatzl, Christine Mian, Christoph H. Klingler, Michael Marberger, The aging lower urinary tract: a comparative urodynamic study of men and women Urology. ,vol. 51, pp. 206- 212 ,(1998) , 10.1016/S0090-4295(97)00616-X
Raymond Rosen, Jens Altwein, Peter Boyle, Roger S Kirby, B Lukacs, Eric Meuleman, Michael P O’Leary, Paolo Puppo, Chris Robertson, Francois Giuliano, Lower urinary tract symptoms and male sexual dysfunction: the multinational survey of the aging male (MSAM-7). European Urology. ,vol. 44, pp. 637- 649 ,(2003) , 10.1016/J.EURURO.2003.08.015