Fitness alteration of foot-and-mouth disease virus mutants: measurement of adaptability of viral quasispecies.
作者： M A Martínez , C Carrillo , F González-Candelas , A Moya , E Domingo
DOI: 10.1128/JVI.65.7.3954-3957.1991
关键词: Mutation 、 Aphthovirus 、 Foot-and-mouth disease virus 、 Biology 、 Viral replication 、 Viral quasispecies 、 Genetics 、 Virus 、 Monoclonal 、 Population 、 Virology
摘要: … MAb SD6 (average of 16 determinations)] represents an underestimate of the mutation rate. … to the relative fitnesses of the mutant and wild type per passage (Table 1). Rapid variation of …
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