Injury-induced decline of intrinsic regenerative ability revealed by quantitative proteomics.

作者: Stephane Belin , Homaira Nawabi , Chen Wang , Shaojun Tang , Alban Latremoliere

DOI: 10.1016/J.NEURON.2015.03.060

关键词: Quantitative proteomicsNeurosciencePI3K/AKT/mTOR pathwayHuntingtinRegeneration (biology)AxotomyBiologySignal transductionAxonRetinal ganglion

摘要: … To better understand their functional interactions, we analyzed the combinatorial effects in the optic nerve injury model by manipulating both c-myc and the mTOR pathway, which was …

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