摘要: Neurons are extremely polarized cells. Axon lengths often exceed the dimension of neuronal cell body by several orders magnitude. These extreme axonal imply that neurons have mastered efficient mechanisms for long distance signaling between soma and synaptic terminal. elaborate required development maintenance nervous system. can fine-tune through calcium wave propagation bidirectional transport proteins, vesicles, mRNAs along microtubules. The signal transmission over also ensures information about axon injury is communicated to allows repair be engaged. This review focuses on different employed distances how signals interpreted in soma, with an emphasis proteomic studies. We discuss approaches could help further deciphering operating axons.
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