Pseudorabies virus expressing bovine herpesvirus 1 glycoprotein B exhibits altered neurotropism and increased neurovirulence.
作者： Volker Gerdts , Jörg Beyer , Béla Lomniczi , Thomas C. Mettenleiter
DOI: 10.1128/JVI.74.2.817-827.2000
关键词: Tissue tropism 、 Virus 、 Pseudorabies 、 Glycoprotein 、 Biology 、 Virology 、 Neurotropism 、 Bovine herpesvirus 1 、 Encephalitis 、 Cell culture
摘要: … We isolated an infectious PrV mutant, PrV-9112C2, which lacks … PrV gB, was able to complement a lethal gB deletion in PrV (37), and PrV gB complemented a gB − herpes simplex virus …
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