The Measurement of Cardiac Membrane Channels following Their Incorporation into Phospholipid Bilayers

作者: A. J. Williams

DOI: 10.1007/978-1-4757-1287-2_5

关键词: SarcolemmaEndoplasmic reticulumMembraneBilayerMembrane channelChemistryPhospholipidVesicleBiochemistryLipid bilayerBiophysics

摘要: This chapter describes the basic properties of integral membrane channels from both cardiac sarcoplasmic reticulum and sarcolemma. Channels are studied, under voltage-clamp conditions, following their incorporation into planar phospholipid bilayers by fusion isolated native vesicles with preformed membranes. The rate may be influenced a number factors including divalent cations negatively charged phospholipids in bilayer.

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