Past, Present, and Future of Affinity-based Cell Separation Technologies
作者： Kaitlyn Bacon , Ashton Lavoie , Balaji M. Rao , Michael Daniele , Stefano Menegatti
DOI: 10.1016/J.ACTBIO.2020.05.004
关键词: Industrial biotechnology 、 Bioprocess 、 Cell sorting 、 Cell isolation 、 Emerging technologies 、 Regenerative medicine 、 Cell separation 、 Computer science 、 Biochemical engineering 、 Biomanufacturing
摘要: Progress in cell purification technology is critical to increase the availability of viable cells for therapeutic, diagnostic, and research applications. A variety of techniques are now available for cell separation, ranging from non-affinity methods such as density gradient centrifugation, dielectrophoresis, and filtration, to affinity methods such as chromatography, two-phase partitioning, and magnetic-/fluorescence-assisted cell sorting. For clinical and analytical procedures that require highly purified cells, the choice of cell purification method is crucial …
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