Carotid Intima Media Thickness and Plaques Can Predict the Occurrence of Ischemic Cerebrovascular Events

作者: Patrizio Prati , Alberto Tosetto , Diego Vanuzzo , Giovanni Bader , Marco Casaroli

DOI: 10.1161/STROKEAHA.107.511584

关键词: IschemiaStrokeIntima-media thicknessCardiologyInternal medicineFramingham Risk ScoreCohortReceiver operating characteristicMedicineSurgeryCohort studyPopulation

摘要: Background and Purpose— The clinical usefulness of noninvasive measurement carotid intima media thickness plaque visualization in the general population is still uncertain. Methods— We evaluated age-specific incidence rates cerebrovascular events a cohort 1348 subjects randomly taken from census list San Daniele Township followed for mean period 12.7 years. association among common thickness, measured at baseline, arterial risk factors, ischemic was modeled using Poisson regression. predictive ability over factors (summarized Framingham Stroke Risk Score) by receiver operating characteristic curve analysis. Results— During follow-up, 115 developed nonfatal stroke, transient attack, or vascular death, which were predefined study end points. After adjustment age sex, hypertension, diabet...

参考文章(37)
P.-J. Touboul, M.G. Hennerici, S. Meairs, H. Adams, P. Amarenco, N. Bornstein, L. Csiba, M. Desvarieux, S. Ebrahim, M. Fatar, R. Hernandez Hernandez, M. Jaff, S. Kownator, P. Prati, T. Rundek, M. Sitzer, U. Schminke, J.-C. Tardif, A. Taylor, E. Vicaut, K.S. Woo, F. Zannad, M. Zureik, Mannheim carotid intima-media thickness consensus (2004-2006). An update on behalf of the Advisory Board of the 3rd and 4th Watching the Risk Symposium, 13th and 15th European Stroke Conferences, Mannheim, Germany, 2004, and Brussels, Belgium, 2006. Cerebrovascular Diseases. ,vol. 23, pp. 75- 80 ,(2007) , 10.1159/000097034
P H Whincup, O Papacosta, S Ebrahim, M Walker, W G Coppola, SCORING SYSTEM TO IDENTIFY MEN AT HIGH-RISK OF STROKE - A STRATEGY FOR GENERAL-PRACTICE British Journal of General Practice. ,vol. 45, pp. 185- 189 ,(1995)
Patrizio Prati, Diego Vanuzzo, Marco Casaroli, Giovanni Bader, Lucio Mos, Lorenza Pilotto, Luigi Canciani, Maurizio Ruscio, Pierre-Jean Touboul, Determinants of Carotid Plaque Occurrence Cerebrovascular Diseases. ,vol. 22, pp. 416- 422 ,(2006) , 10.1159/000094993
N J Wald, A K Hackshaw, C D Frost, When can a risk factor be used as a worthwhile screening test BMJ. ,vol. 319, pp. 1562- 1565 ,(1999) , 10.1136/BMJ.319.7224.1562
Georgios Tsivgoulis, Konstantinos Vemmos, Christos Papamichael, Konstantinos Spengos, Efstathios Manios, Kimon Stamatelopoulos, Demetrios Vassilopoulos, Nikolaos Zakopoulos, Common Carotid Artery Intima-Media Thickness and the Risk of Stroke Recurrence Stroke. ,vol. 37, pp. 1913- 1916 ,(2006) , 10.1161/01.STR.0000226399.13528.0A
Pierre-Jean Touboul, Patrizio Prati, Pierre-Yves Scarabin, Valérie Adrai, Emmanuel Thibout, Pierre Ducimetière, Use of monitoring software to improve the measurement of carotid wall thickness by B-mode imaging. Journal of Hypertension. ,vol. 10, ,(1992) , 10.1097/00004872-199207001-00006
Hanna Tolonen, Markku Mähönen, Kjell Asplund, Daiva Rastenyte, Kari Kuulasmaa, Diego Vanuzzo, Jaakko Tuomilehto, Do Trends in Population Levels of Blood Pressure and Other Cardiovascular Risk Factors Explain Trends in Stroke Event Rates Stroke. ,vol. 33, pp. 2367- 2375 ,(2002) , 10.1161/01.STR.0000033131.27936.7F
L. E. Chambless, A. R. Folsom, L. X. Clegg, A. R. Sharrett, E. Shahar, F. J. Nieto, W. D. Rosamond, G. Evans, Carotid Wall Thickness is Predictive of Incident Clinical Stroke: The Atherosclerosis Risk in Communities (ARIC) Study American Journal of Epidemiology. ,vol. 151, pp. 478- 487 ,(2000) , 10.1093/OXFORDJOURNALS.AJE.A010233
P Prati, D Vanuzzo, M Casaroli, A Di Chiara, F De Biasi, G A Feruglio, P J Touboul, Prevalence and determinants of carotid atherosclerosis in a general population. Stroke. ,vol. 23, pp. 1705- 1711 ,(1992) , 10.1161/01.STR.23.12.1705
M. ROSVALL, L. JANZON, G. BERGLUND, G. ENGSTROM, B. HEDBLAD, Incident coronary events and case fatality in relation to common carotid intima-media thickness. Journal of Internal Medicine. ,vol. 257, pp. 430- 437 ,(2005) , 10.1111/J.1365-2796.2005.01485.X