ZOT-derived peptide and chitosan functionalized nanocarrier for oral delivery of protein drug.
作者： Jong Hyun Lee , Abhishek Sahu , Won Il Choi , Jae Young Lee , Giyoong Tae
DOI: 10.1016/J.BIOMATERIALS.2016.06.059
关键词: Biophysics 、 Insulin 、 Small intestine 、 Tight junction 、 Nanocarriers 、 Chitosan 、 Materials science 、 Biomedical engineering 、 Paracellular transport 、 Ligand (biochemistry) 、 Peptide
摘要: In this study, we developed a dual ligand functionalized pluronic-based nanocarrier (NC) for oral delivery of insulin. Chitosan and zonula occludins toxin (ZOT)-derived, tight junction …
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