Comparison of the Directigen Flu A+B Membrane Enzyme Immunoassay with Viral Culture for Rapid Detection of Influenza A and B Viruses in Respiratory Specimens

作者: A. C. Cazacu , S. E. Chung , J. Greer , G. J. Demmler

DOI: 10.1128/JCM.42.8.3707-3710.2004

关键词: Viral cultureRapid detectionVirus detectionVirologyViral diseaseRespiratory systemImmunoassayInfluenza aMedicineEnzyme

摘要: The performance of a commercially available, rapid membrane enzyme immunoassay for influenza A and B virus detection was compared to that viral culture in 4,092 respiratory specimens collected from patients presenting with symptoms during the 2002-2003 season. test's overall sensitivity 43.83%, lower than previously reported but similar both viruses (42.98 versus 44.76%). However, specificity, 99.74%, excellent (99.82 99.92%). These values make this test very good confirmatory when clinical suspicion is high, less accurate screening large populations.

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