作者: Yusuke Higaki , Masato Kobayashi , Tomoya Uehara , Hirofumi Hanaoka , Yasushi Arano
DOI: 10.1007/S12149-012-0681-5
关键词: Nuclear medicine 、 Pinhole (optics) 、 Image resolution 、 Scanner 、 Collimator 、 Small animal 、 Spect imaging 、 Image quality 、 Planar Imaging 、 Medicine
摘要: Almost all small animal SPECT is performed with pinhole collimators (PH), including single-PH (SPH) and multi-PH (MPH). In the clinical study, not only PH but also parallel-hole collimator (PAH) often used in planar imaging. However, there have been no comparative studies on image quality various This study compared basic characteristics of PAH Performance images was evaluated using 99mTcO4 − SPH, MPH low energy high resolution SPECT/CT scanner FX3200. We measured sensitivity, resolution, concentration linearity uniformity. Planar imaging mice 99mTc-labeled mercaptoacetyltriglycine (99mTc-MAG3) SPH PAH. 99mTc-methylene diphosphonate (99mTc-MDP) collimators. With PAH, sensitivity 43.5, 211.2 926.5 cps/MBq, respectively, spatial 0.60/0.56, non/0.96, 5.20/5.34 mm full-width half maximum (planar/SPECT), respectively. There were marked correlations between radioactivity counts Values % standard deviation showed differences while values smallest MPH. On mice, yielded high-quality 99mTc-MAG3-planar when sharper 99mTc-MDP-SPECT than The differed Although higher resolution. Among collimators, more appropriate for imaging, suitable a CZT detector.