Feline muscular dystrophy with dystrophin deficiency.

作者: John F. Rae , Eric P. Hoffman , Louis M. Kunkel , James J. Dasbach , Laurie K. Pearce

DOI:

关键词: Duchenne muscular dystrophyEndocrinologyBiologyCarnivoraDystrophinX chromosomeCATSMuscular dystrophyMuscle hypertrophyInternal medicineITGA7

摘要: Abstract This is the first description of a dystrophin-Deficient muscular dystrophy in domestic cats. The disorder appears to be X-linked inheritance because it affected both males litter four kittens. Immunoblotting and immunofluorescent detection dystrophin showed present control cat muscle but no detectable either cat. feline was progressive histopathologically resembled human Duchenne/Becker except for lack fat infiltration presence prominent hypertrophy fibers muscles groups disorder.

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