Microelectrode recording of cerebellar and cerebral unit activity during convulsive afterdischarge.

摘要: Abstract Cerebellar unitary discharge has been recorded with microelectrodes from cerebellar cortex and nuclei before, during, after different convulsive patterns induced in curarized rats by electrical stimulation of the brain, intraperitoneal injection convulsant drugs (Megimide or Metrazol), anoxia. It compared simultaneously activity cerebral (sensorimotor area) either concentric electrodes. Low-voltage, single repetitive sensorimotor area are incapable modifying discharge. They show an increase frequency only strong shocks stimulation. During anoxia units acceleration a short latency afterwards they become silent. The also but usually continue to be active even when cerebrum is After drugs, such as Megimide Metrazol, exhibit first at time brain still normal. At significantly later rate increases. In some cases each high-voltage slow wave accompanied units. clonic period depressed begin again end seizure totally cerebellum may actively inhibit activity.