Ervatamia coronaria: chemical constituents and some pharmacological activities
作者： A.T. Henriques , A.A. Melo , P.R.H. Moreno , L.L. Ene , J.A.P. Henriques
DOI: 10.1016/0378-8741(95)01328-8
关键词: Pentobarbital 、 Pharmacognosy 、 Salicylic acid 、 Apocynaceae 、 Traditional medicine 、 Alkaloid 、 Coronaridine 、 Medicine 、 Biological activity 、 Anti-inflammatory
摘要: A new bisindole alkaloid, 19,20-dihydroervahanine was isolated from the stems of Ervatamia coronaria grown in Brazil, together with five known alkaloids: coronaridine, heyneanine, voacristine, voacamine, descarbomethoxyvoacamine and phenolic acids: vanillic, gentisic, syringic, 4-hydroxybenzoic salicylic acid. The aqueous alcoholic extracts, when administered p.o. or i.p. to rats 1 h before subplantar injection carrageenin had a significant anti-inflammatory effect. extract also an analgesic effect increased pentobarbital induced sleeping time.
elsevier.com
sci-hub.se 参考文章(27)
Maeda H, Ishida N, Kumagai K, Characterization of neocarzinostatin. The Journal of Antibiotics. ,vol. 19, pp. 253- 259 ,(1966)
Robert A Chalmers, O Mikes, Laboratory handbook of chromatographic methods Van Nostrand. ,(1966)
Toh-Seok Kam, Kah-Yeng Loh, Lay-Har Lim, Wai-Ling Loong, Cheng-Hock Chuah, Chen Wei, New alkaloids from the leaves of Tabernaemontana divaricata Tetrahedron Letters. ,vol. 33, pp. 969- 972 ,(1992) , 10.1016/S0040-4039(00)91590-9
C. A. Winter, E. A. Risley, G. W. Nuss, Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs Experimental Biology and Medicine. ,vol. 111, pp. 544- 547 ,(1962) , 10.3181/00379727-111-27849
Xiao-Zbang Feng, Gui Liu, Christiane Kan, Pierre Potier, Siew-Kwong Kan, New Dimetic Indole Alkaloids fron Ervatamia Bainanensis Journal of Natural Products. ,vol. 52, pp. 928- 933 ,(1989) , 10.1021/NP50065A003
A.A. Melo, C.B. Querol, A.T. Henriques, J.A.P. Henriques, Cytostatic, cytotoxic and mutagenic effects of voacristine, an indole alkaloid in wild-type and repair-deficient yeasts Mutation Research/Genetic Toxicology. ,vol. 171, pp. 17- 24 ,(1986) , 10.1016/0165-1218(86)90004-2
Bani Talapatra, Amarendra Patra, Talapatra Sunil K, Terpenoids and alkaloids of the leaves of Tabernaemontana coronaria Phytochemistry. ,vol. 14, pp. 1652- 1653 ,(1975) , 10.1016/0031-9422(75)85375-1
Atta-ur-Rahman Atta-ur-Rahman, KA Alvi, A Muzaffar, None, Isolation and 1H/13C-NMR Studies on 19,20-Dihydrocondylocarpine: An Alkaloid from the Leaves of Ervatamia coronaria and Alstonia scholaris. Planta Medica. ,vol. 52, pp. 325- 326 ,(1986) , 10.1055/S-2007-969167
E. Mousstacchi, V. Favaudon, Cytotoxic and mutagenic effects of neocarzinostatin in wild-type and repair-deficient yeasts. Mutation Research Letters. ,vol. 104, pp. 87- 94 ,(1982) , 10.1016/0165-7992(82)90125-7
Denise Dagnino, Jan Schripsema, Anja Peltenburg, Robert Verpoorte, Kees Teunis, Capillary gas chromatographic analysis of indole alkaloids : investigation of the indole alkaloids present in Tabernaemontana divaricata cell suspension culture Journal of Natural Products. ,vol. 54, pp. 1558- 1563 ,(1991) , 10.1021/NP50078A010