Rage-related methods and compositions for treating glomerular injury

作者: Ann Marie Schmidt , Vivette D'agati

DOI:

关键词: Internal medicineBlockadeEndocrinologyRage (emotion)Medicine

摘要: This invention provides methods, compositions and articles of manufacture for inhibiting the onset treating glomerular injury. The instant is based on blockade RAGE and/or G82S function.

参考文章(6)
Ann Marie Schmidt, David M. Stern, Method for treating symptoms of diabetes ,(1997)
Thoralf M. Wendt, Nozomu Tanji, Jiancheng Guo, Thomas R. Kislinger, Wu Qu, Yan Lu, Loredana G. Bucciarelli, Ling Ling Rong, Bernhard Moser, Glen S. Markowitz, Gunther Stein, Angelika Bierhaus, Birgit Liliensiek, Bernd Arnold, Peter P. Nawroth, David M. Stern, Vivette D. D'Agati, Ann Marie Schmidt, RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. American Journal of Pathology. ,vol. 162, pp. 1123- 1137 ,(2003) , 10.1016/S0002-9440(10)63909-0
Thoralf Wendt, Nozomu Tanji, Jiancheng Guo, Barry I Hudson, Angelika Bierhaus, Ravichandran Ramasamy, Bernd Arnold, Peter P Nawroth, Shi Fang Yan, Vivette D’Agati, Ann Marie Schmidt, Glucose, Glycation, and RAGE: Implications for Amplification of Cellular Dysfunction in Diabetic Nephropathy Journal of The American Society of Nephrology. ,vol. 14, pp. 1383- 1395 ,(2003) , 10.1097/01.ASN.0000065100.17349.CA
Kevan Herold, Ann Marie Schmidt, David M. Stern, Shi Du Yan, Ira Lamster, Methods for treating inflammation ,(2007)