Method for treating symptoms of diabetes
作者： Ann Marie Schmidt , David M. Stern
DOI:
关键词: Internal medicine 、 Diabetes mellitus 、 Endocrinology 、 Advanced Glycation Endproducts 、 Medicine 、 Bioinformatics
摘要: The present invention provides a method for treating symptoms of diabetes in diabetic subject which comprises administering to the therapeutically effective amount an agent inhibits binding advanced glycation endproducts any receptor so as treat chronic subject.
lens.org 参考文章(37)
Z Makita, R Bucala, H Shiiki, T Nishino, K Dohi, Y Nakamura, H Vlassara, T Kagoshima, Y Horii, Y Sakaguchi, Immunohistochemical localization of advanced glycosylation end products in coronary atheroma and cardiac tissue in diabetes mellitus. American Journal of Pathology. ,vol. 143, pp. 1649- 1656 ,(1993)
U Ritthaler, Y Deng, Y Zhang, J Greten, M Abel, B Sido, J Allenberg, G Otto, H Roth, A Bierhaus, R Ziegler, A-M Schmidt, R Waldherr, P Wahl, DM Stern, PP Nawroth, Expression of receptors for advanced glycation end products in peripheral occlusive vascular disease. American Journal of Pathology. ,vol. 146, pp. 688- 694 ,(1995)
Bucala R, Vlassara H, Striker L, Pathogenic Effects of Advanced Glycosylation: Biochemical, Biologic, and Clinical Implications for Diabetes and Aging Laboratory Investigation. ,vol. 70, pp. 138- 151 ,(1994)
Martin Grumet, Method of promoting wound healing and scar regression ,(1994)
Zhi Yang, Helen Vlassara, Anthony Cerami, Liver-derived receptors for advanced glycosylation endproducts and uses thereof ,(1991)
Ann Marie Schmidt, David Stern, Methods for determining whether a compound is capable of inhibiting the interaction of a peptide with rage ,(1999)
M Neeper, A.M. Schmidt, J Brett, S.D. Yan, F Wang, Y.C. Pan, K Elliston, D Stern, A Shaw, Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. Journal of Biological Chemistry. ,vol. 267, pp. 14998- 15004 ,(1992) , 10.1016/S0021-9258(18)42138-2
A.M. Schmidt, R. Mora, R. Cao, S.D. Yan, J. Brett, R. Ramakrishnan, T.C. Tsang, M. Simionescu, D. Stern, The endothelial cell binding site for advanced glycation end products consists of a complex: an integral membrane protein and a lactoferrin-like polypeptide. Journal of Biological Chemistry. ,vol. 269, pp. 9882- 9888 ,(1994) , 10.1016/S0021-9258(17)36965-X
Ann Marie Schmidt, David Stern, METHOD TO PREVENT ACCELERATED ATHEROSCLEROSIS USING (sRAGE) SOLUBLE RECEPTOR FOR ADVANCED GLYCATION ENDPRODUCTS ,(1998)
A.M. Schmidt, M Vianna, M Gerlach, J Brett, J Ryan, J Kao, C Esposito, H Hegarty, W Hurley, M Clauss, Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface. Journal of Biological Chemistry. ,vol. 267, pp. 14987- 14997 ,(1992) , 10.1016/S0021-9258(18)42137-0