Chronic Periaortitis as a Systemic Autoimmune Disease

摘要: Chronic periaortitis is an idiopathic disease whose hallmark the presence of a fibro-inflammatory tissue arising from adventitia abdominal aorta and common iliac arteries extending into surrounding retroperitoneum frequently encasing neighboring structures such as ureters inferior vena cava (Mitchinson, 1984; Parums, 1990). It should be regarded generalized with three different pathophysiological entities, specifically retroperitoneal fibrosis, inflammatory aortic aneurysms, perianeurysmal fibrosis (Vaglio et al., 2003; Jois 2004). Idiopathic characterized by periaortic fibroinflammatory tissue, which often causes obstruction other adjacent 1970; Gilkeson & Allen, 1996). A dilated usually not present in fibrosis. Its initial signs symptoms are nonspecific, malaise, anorexia, weight loss, fever, flank, back, or pain. Inflammatory aneurysms characteristically develop mass around aorta, but do cause obstructions (Crawford 1985; Pennell 1985). presents typical triad back pain, pulsatile sometimes tender mass, elevated erythrocyte sedimentation rate. Perianeurysmal represents link between these two diagnoses, involves surrounded that encases organs (Serra al, 1980). These definitions may little confusing, it would probably more appropriate to distinguish aneurysmal nonaneurysmal forms chronic periaortitis; referred non-aneurysmal periaortitis, where 2006). important diagnose early its course order attempt prevent severe secondary complication renal failure due ureteric potentially fatal consequence rupture (Jois Although most studies have considered entities separately, conditions clinical histopathologic findings, thus represent manifestations same disease.