Multicenter Evaluation of the Bovine Mesenteric Vein Bioprostheses for Hemodialysis Access in Patients with an Earlier Failed Prosthetic Graft

作者: Howard E. Katzman , Marc H. Glickman , A. Frederick Schild , Roy M. Fujitani , Jeffrey H. Lawson

DOI: 10.1016/J.JAMCOLLSURG.2005.03.040

关键词: SurgeryThrombosisMesenteric VeinVascular PatencyMedicineProsthesisHemodialysisPredictive value of testsProportional hazards modelClinical trial

摘要: Background The number of patients requiring hemodialysis increases each year, with a large cohort still prosthetic grafts for hemodialysis. All available vascular access have predictable failure rates, leading to group multiple failed grafts. This report evaluates use mesenteric vein bioprosthesis (MVB) as conduit who at least one earlier synthetic graft. Study design Two-hundred seventy-six were implanted in had Of these grafts, 183 MVB and 93 synthetic. Graft histories obtained from 128 the received MVB, representing nonrandomized historic data set previously an internal control (INT). Patency was determined by Kaplan-Meier analysis, Cox proportional hazards model used multivariate analysis factors predictive effect. Results Primary patency 12 months 35.6% versus 28.4% At 24 months, secondary 60.3% 42.9% synthetic, 18.0% INT (p Conclusions provided superior graft compared both or newly implants. A considerable reduction thrombosis, infection, interventions observed These results suggest that offers safe alternative history failing may represent option extending this patient population.

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