Brain changes during the onset of schizophrenia: implications for neurodevelopmental theories.
作者： Stephen J Wood , Christos Pantelis , Alison R Yung , Dennis Velakoulis , Patrick D McGorry
DOI: 10.5694/J.1326-5377.2009.TB02367.X
关键词: Psychotic illness 、 Medicine 、 Psychiatry 、 Ultra high risk 、 Age of onset 、 Neuroimaging 、 Psychosis 、 Schizophrenia 、 Chronic exposure 、 Predictive value
摘要: Neuroimaging studies of individuals at risk psychosis have the potential to identify markers predictive illness onset and features that progress with transition. To date, reduced brain volumes shown weak value for psychotic illness. All published longitudinal transition show progressive changes are not seen in at-risk who do develop disorder. Although cause these is unclear, they challenge conventional neurodevelopmental model schizophrenia.
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