Simulated assembly line performance following ingestion of cetirizine or hydroxyzine.

摘要: Twelve healthy subjects participated in three daytime work periods, a double-blind repeated measures Latin square design. Subjects received cetirizine (10 mg), hydroxyzine (25 or placebo at 0800. Performance was measured each day during eight 50-minute test periods on simulated assembly line task between 0830 and 1700. Before entry into the study, were trained to minimum 80% correction rate performance task. decrements consistently associated with but not cetirizine. made fewer correct responses compared both placebo. Subjectively, participants reported feeling sleepier performing worse condition than following Cetirizine, however, did differ from other two conditions self-assessments of alertness performance. These findings support hypothesis that objective human functioning are more specific subjective measures.