Control randomized study of rehydration/rehydration with dioctahedral smectite in ambulatory Thai infants with acute diarrhea

摘要: The study was performed to assess the efficiency, acceptability and safety of dioctahedral smectite (DS) associated with rehydration in ambulatory infants acute diarrhea. Sixty-six Thai infants, aged 1-24 months were randomly divided into 2 groups. One group 32 (control group) received oral or intravenous rehydration, other 34 (DS DS. Both groups comparable for sex, age, weight, diet, duration diarrhea, body temperature, nutritional dehydration status. Bacteriological stool examination positive 22% control 26% DS Salmonella, Shigella, Campylobacter, enterotoxigenic Escherichia coli Plesiomonas sp. Rotavirus found 25% 29% group. Seventy-two hours after therapy, 34% cured compared 71% (p < 0.01) 5 days beginning treatment, still had diarrhea 12% = 0.04). considered be good 30 (88%). No major side effect observed. In conclusion, shortens course may reduce occurrence prolonged is well tolerated