Altered trabecular bone morphology in adolescent and young adult athletes with menstrual dysfunction.

摘要: Abstract Context Young amenorrheic athletes (AA) have lower bone mineral density (BMD) and an increased prevalence of fracture compared with eumenorrheic (EA) non-athletes. Trabecular morphology is a determinant skeletal strength may contribute to risk. Objectives To determine the variation in trabecular among AA, EA, non-athletes association AA. Design setting A cross-sectional study performed at academic clinical research center. Participants 161 girls young women aged 14–26 years (97 32 non-athletes). Main outcome measure We measured volumetric BMD (vBMD) microarchitecture using high-resolution peripheral quantitative computed tomography. evaluated (plate-like vs. rod-like), orientation, connectivity by individual trabecula segmentation. Results At non-weight-bearing distal radius, groups did not differ for vBMD. However, plate-like volume fraction (pBV/TV) was AA EA (p = 0.03), as were plate number (p = 0.03) (p = 0.03). weight-bearing tibia, vBMD higher (p = 0.05 p = 0.009 non-athletes, respectively). pBV/TV (p = 0.04 p = 0.005 non-athletes), axially-aligned trabeculae, number, connectivity. Among those history recurrent stress had pBV/TV, thickness, radius. Conclusions alignment These differences be associated