Differences in Trabecular Microstructure Between Black and White Women Assessed by Individual Trabecular Segmentation Analysis of HR‐pQCT Images

摘要: Black women have lower fracture risk compared with white women, which may be partly explained by improved volumetric bone mineral density (vBMD) and microarchitecture primarily within the cortical compartment. To determine if there are differences in trabecular microstructure, connectivity, alignment according to race/ethnicity, we performed individual segmentation (ITS) analyses on high-resolution peripheral quantitative computed tomography (HR-pQCT) scans of distal radius tibia 273 peri- postmenopausal black (n = 100) (n = 173) participating Study Women's Health Across Nation Boston. Unadjusted showed that had greater plate volume fraction, thickness, number density, surface area along axial trabeculae, whereas rod tissue fraction (p < 0.05 for all). Adjustment clinical covariates augmented these race/ethnicity-related plates rods, such rod-rod continued superior structural characteristics These remained significant after adjustment hip BMD vBMD. In conclusion, more plate-like morphology higher rod-like trabeculae. contribute strength observed women. © 2016 American Society Bone Mineral Research.