Epinephrine and vasopressin during cardiopulmonary resuscitation

摘要: Abstract Epinephrine (adrenaline) and vasopressin have been by far the most commonly studied vasopressors in experimental cardiac arrest. Despite animal studies suggesting improved outcomes arrest, clinical trials of pressor agents failed to show clear cut benefit from either or epinephrine, although few, if any, compared a placebo. The action heart, particularly β 1 -Adrenergic stimulation, is associated with adverse effects including post-resuscitation myocardial dysfunction, worsening ventricular arrhythmias, increasing oxygen consumption. α 2 agonists, studies, great promise improving but not humans. combination epinephrine may be effective, has incompletely studied. Clinical vasopressor agents, which minimize direct are needed.