New Paradigms in the Pathogenesis of Chronic Obstructive Pulmonary Disease I

作者: W. MacNee , R. M. Tuder

DOI: 10.1513/PATS.200905-027DS

关键词: SenescenceImmunologyPulmonary diseasePathogenesisOxidative stressMedicineCOPD

摘要: This paper reviews the potential participation of novel pathogenic mechanisms in chronic obstructive pulmonary disease (COPD) relating to aging, including oxidative stress and …

参考文章(69)
R. M. Tuder, Cellular and Molecular Mechanisms of Alveolar Destruction in Emphysema: An Evolutionary Perspective Proceedings of the American Thoracic Society. ,vol. 3, pp. 503- 510 ,(2006) , 10.1513/PATS.200603-054MS
Kazutetsu Aoshiba, Atsushi Nagai, Takao Tsuji, ALVEOLAR CELL SENESCENCE IN PULMONARY EMPHYSEMA PATIENTS ,(2006)
Tao Zheng, Min Jong Kang, Kristina Crothers, Zhou Zhu, Wei Liu, Chun Geun Lee, Lesley A Rabach, Harold A Chapman, Robert J Homer, David Aldous, George DeSanctis, Stephen Underwood, Michael Graupe, Richard A Flavell, John A Schmidt, Jack A Elias, None, Role of Cathepsin S-Dependent Epithelial Cell Apoptosis in IFN-γ-Induced Alveolar Remodeling and Pulmonary Emphysema Journal of Immunology. ,vol. 174, pp. 8106- 8115 ,(2005) , 10.4049/JIMMUNOL.174.12.8106
Thomas von Zglinicki, Alexander Bürkle, Thomas BL Kirkwood, Stress, DNA damage and ageing -- an integrative approach. Experimental Gerontology. ,vol. 36, pp. 1049- 1062 ,(2001) , 10.1016/S0531-5565(01)00111-5
Yukio Ishii, Ken Itoh, Yuko Morishima, Toru Kimura, Takumi Kiwamoto, Takashi IIzuka, Ahmed E. Hegab, Tomonori Hosoya, Akihiro Nomura, Tohru Sakamoto, Masayuki Yamamoto, Kiyohisa Sekizawa, Transcription Factor Nrf2 Plays a Pivotal Role in Protection against Elastase-Induced Pulmonary Inflammation and Emphysema Journal of Immunology. ,vol. 175, pp. 6968- 6975 ,(2005) , 10.4049/JIMMUNOL.175.10.6968
K-C Müller, L Welker, K Paasch, B Feindt, VJ Erpenbeck, JM Hohlfeld, N Krug, M Nakashima, D Branscheid, H Magnussen, RA Jörres, O Holz, Lung fibroblasts from patients with emphysema show markers of senescence in vitro Respiratory Research. ,vol. 7, pp. 32- 32 ,(2006) , 10.1186/1465-9921-7-32
Wei Liu, Masashi Kato, Anwaral A Akhand, Akemi Hayakawa, Haruhiko Suzuki, Toshio Miyata, Kiyoshi Kurokawa, Yoshihiro Hotta, Naohisa Ishikawa, Izumi Nakashima, None, 4-hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death. Journal of Cell Science. ,vol. 113, pp. 635- 641 ,(2000) , 10.1242/JCS.113.4.635
Rubin M. Tuder, Irina Petrache, Jack A. Elias, Norbert F. Voelkel, Peter M. Henson, Apoptosis and emphysema: the missing link. American Journal of Respiratory Cell and Molecular Biology. ,vol. 28, pp. 551- 554 ,(2003) , 10.1165/RCMB.F269
Gabriele Saretzki, Thomas Von Zglinicki, None, Replicative aging, telomeres, and oxidative stress. Annals of the New York Academy of Sciences. ,vol. 959, pp. 24- 29 ,(2002) , 10.1111/J.1749-6632.2002.TB02079.X
Laurent Savale, Ari Chaouat, Sylvie Bastuji-Garin, Elisabeth Marcos, Laurent Boyer, Bernard Maitre, Mourad Sarni, Bruno Housset, Emmanuel Weitzenblum, Mireille Matrat, Philippe Le Corvoisier, Dominique Rideau, Jorge Boczkowski, Jean-Luc Dubois-Randé, Christos Chouaid, Serge Adnot, Shortened telomeres in circulating leukocytes of patients with chronic obstructive pulmonary disease. american thoracic society international conference. ,vol. 179, pp. 566- 571 ,(2009) , 10.1164/RCCM.200809-1398OC