Suppression of withdrawal symptoms by dynorphin in heroin addicts
作者： Hsiang Lai Wen , Walter K.K. Ho
DOI: 10.1016/0014-2999(82)90509-X
关键词: Anesthesia 、 Formication 、 Feeling 、 HEROIN WITHDRAWAL 、 Saline 、 Dynorphin 、 Psychology 、 Placebo 、 Precordial examination 、 Heroin addicts 、 Pharmacology
摘要: Abstract The effectiveness of dynorphin-(1–13) in suppressing heroin withdrawal was studied. At a dose 60 μg/kg body weight, effective symptoms. When saline administered strong placebo effect noticed that, however, did not influence the outcome results. Only three out twelve patients receiving experienced some mild side-effects such as feeling warm, dizziness and precordial formication.
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