Population inhalation exposure to polycyclic aromatic hydrocarbons and associated lung cancer risk in Beijing region: Contributions of indoor and outdoor sources and exposures

作者: Bin Zhou , Bin Zhao

DOI: 10.1016/J.ATMOSENV.2012.08.059

关键词: Lung cancerAttributable riskInhalation exposureBeijingEnvironmental sciencePah exposurePopulationEnvironmental chemistryPollutantConfidence intervalEnvironmental health

摘要: Abstract Polycyclic aromatic hydrocarbons (PAHs) are among the most toxic air pollutants in China. Efforts assessing population inhalation exposure to PAHs, and its contribution lung cancer risk for Chinese residents, have been limited due insufficient data on measured indoor concentrations. A mass-balance model predict PAH concentrations was developed, along with estimated exposures attributable risks residents Beijing region 2006, a 2-stage Monte Carlo simulation framework. The were split into three parts, based sources places of exposure, estimate contributions outdoor exposures, order better understand source place pattern exposure. PAHs bring considerable region. fraction (PAF) Beijing's overall is 2.99% [95% confidence interval (CI): 1.71%–4.26%]. Median outdoor-originated (OUT–in) 78% (CI: 73%–81%) population, 97% 94%–99%) whom OUT–in largest contributor. Rural facing indoor-originated (IN–in), which dominates total 12% 2%–24%) rural population. This framework could be used quantitative comparison different interventions as well other airborne pollutants.

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