作者: Joel Guss , Erica R. Thaler
DOI: 10.1007/978-0-387-73062-2_16
关键词: Sinusitis 、 Paranasal sinuses 、 rhinorrhea 、 Otitis 、 Medicine 、 Environmental exposure 、 Pediatrics 、 Asthma 、 Nasal congestion 、 Nose
摘要: Rhinosinusitis refers to any inflammatory condition of the nose and paranasal sinuses. Although terms rhinitis sinusitis are often used independently, term rhinosinusitis reflects an understanding that most pathological processes will affect entire mucous membrane represents a heterogeneous group diseases is end result myriad pathophysiological include infection, allergy, autoimmunity, environmental exposure, structural abnormalities, hormonal effects, genetic disease. The interaction multiple in each individual patient further complicates management very common. Approximately 32 million adults United States received diagnosis 1998, reflecting 16% adult population [1]. 40 Americans estimated be affected by allergic year, with half these experiencing symptoms during 4 or more months year [2]. direct health care costs associated exceed $6 billion annually indirect cost rhinosinusitis, including missed days work school decreased productivity while at work, may far even this number. Further, figures do not account for treating possible complications such as asthma, otitis media, sleep-disordered breathing. also has profound impact on quality life long been overlooked. For example, 2006 large-scale survey patients found 40% thought disease impacted their “moderate amount” “a lot” [3]. While nasal congestion, postnasal drip, rhinorrhea, headache were labeled “extremely bothersome” largest number subjects, psychosocial morbidity appeared great well. Forty-four percent claimed they frequently tired allergy season, 29% 13%, respectively, felt miserable depressed.