Effectiveness of oral and intravenous iron therapy in haemodialysis patients.

作者: C.-C Jenq , Y.-C. Tian , H.-H. Wu , P.-Y. Hsu , J.-Y. Huang

DOI: 10.1111/J.1742-1241.2006.01166.X

关键词: PillIron deficiencySurgeryGastroenterologyOral administrationFerricAnemiaHemodialysisInternal medicineHematocritComplicationMedicine

摘要: Anaemia is a common and serious complication in patients with end-stage renal disease. Iron therapy crucial managing anaemia maintenance of haemodialysis (HD) patients. This study investigated the efficacy both oral intravenous (i.v.) therapies, possible factors deleteriously affecting patient response to iron therapy. Forty on HD from single institution were enrolled this 6-month retrospective study. Group I (n = 20) received i.v. two ampoules atofen (ferric chloride hexahydrate 193.6 mg) per week for total 6 weeks (total dosage, 960 mg). II ferrous sulphate S.C. Tab (ferrous 324 one pill three times daily 63,000 Patients whose haematocrit (Hct) level increased at minimum 3% within period classified as responders. ferric (960 was more effective than (63,000 correcting deficiency. In group I, serum triglyceride (TG) levels significantly lower responding no response. II, high-sensitive C-reactive protein (hs-CRP) The treating Serum hs-CRP TG may be parameters predicting hyporesponsiveness respectively.

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