Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints.
作者： Mahesh K. B. Parmar , Valter Torri , Lesley Stewart
DOI: 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8
关键词: Statistics 、 Event (probability theory) 、 Hazard ratio 、 Computer science 、 Reliability (statistics) 、 Summary statistics 、 Meta-Analysis as Topic 、 Variance (accounting) 、 Hazard (logic) 、 Data mining 、 Proportional hazards model
摘要: Meta‐analyses aim to provide a full and comprehensive summary of related studies which have addressed a similar question. When the studies involve time to event (survival‐type) data the most appropriate statistics to use are the log hazard ratio and its variance. However, these are not always explicitly presented for each study. In this paper a number of methods of extracting estimates of these statistics in a variety of situations are presented. Use of these methods should improve the efficiency and reliability of meta‐analyses of the published …
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