Prediction and Optimization of Pharmacokinetic and Toxicity Properties of the Ligand.
作者： Douglas E. V. Pires , Lisa M. Kaminskas , David B. Ascher
DOI: 10.1007/978-1-4939-7756-7_14
关键词: Drug 、 Biochemical engineering 、 In silico 、 Drug development 、 Computer science 、 Prioritization 、 Pharmacokinetics
摘要: … Here we demonstrate the use of the comprehensive analysis system pkCSM, to allow early identification of potential problems, prioritization of hits, and optimization of leads. …
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