Effect of Branched-Chain Keto-acids and Dietary Protein Content on the Activity of Branched-Chain Amino Acid Transferase in Rat Tissues

摘要: Rats fed branched-chain keto-acids in place of amino acids exhibited increased specific activity acid transferase (BATase) muscle, intestine, brain and liver as compared with controls sufficient diet to achieve comparable weight gain. This increase was observed whether or not methionine phenylalanine were also replaced by their N-free analogues. Kidney BATase unaffected. a protein-free higher kidney, brain, intestine than rats diets containing 6% casein; but little change these organs seen casein intake progressively from 18%. Muscle the same between 0 18% dietary casein. The results show that keto-analogues augment several tissues, including muscle. In contrast, varying had effect, although protein-feeding augments some organs.