Chromatin-interaction compartment switch at developmentally regulated chromosomal domains reveals an unusual principle of chromatin folding

作者: S.-i. Takebayashi , V. Dileep , T. Ryba , J. H. Dennis , D. M. Gilbert

DOI: 10.1073/PNAS.1207185109

关键词: Chromatin remodelingChromosome conformation captureDNA replicationChIA-PETGeneticsCompartment (development)ChromatinOrigin recognition complexReplication timingBiologyCell biology

摘要: … domain model of replication-timing regulation. Our results reveal a principle of developmentally … involving a subnuclear compartment switch of inaccessible chromatin. This unusual level …

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