Role of the Murine Reprogramming Factors in the Induction of Pluripotency
作者： Rupa Sridharan , Jason Tchieu , Mike J. Mason , Robin Yachechko , Edward Kuoy
DOI: 10.1016/J.CELL.2009.01.001
关键词: Stem cell 、 Cell potency 、 Induced pluripotent stem cell 、 Reprogramming 、 SOX2 、 Cell biology 、 Embryonic stem cell 、 Cellular differentiation 、 Rex1 、 Biology 、 General Biochemistry, Genetics and Molecular Biology
摘要: Induced pluripotent stem (iPS) cells can be obtained from fibroblasts upon expression of Oct4, Sox2, Klf4, and c-Myc. To understand how these factors induce pluripotency, we carried …
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